Capsaicin promotes the development of burst-forming nits-erythroid (BFU-E) from mouse bone marrow cells

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pluripoietin, supports colony formation of normal human bone marrow in vitro from muitipotential (colony forming unit of granulocytes/erythrocytes/macrophages/megakaryocytes [CFU-GEMM]) and early erythroid (burst forming unit of erythroid cells [BFU-E]) progenitors, as

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Bone Marrow With Erythroid Burst-promoting Properties

Several laboratories have demonstrated a requirement for burst-promoting activity (BPA), a product of T cells, or T cell/ monocyte collaboration in the induction of differentiation of peripheral blood erythroid burst-forming units (BFU-E) in vitro. The physiologic significance of this finding is brought into question by patients with severe mature T cell deficiency who have normal in vivo eryth...

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In vivo erythropoietin requirements of regenerating erythroid progenitors (BFU-e, CFU-e) in bone marrow of mice.

Erythroid progenitors (B-8, B-4, CFU-e) in the femoral marrow of polycythemic mice were measured by in vitro culture assays after a single administration of BCNU or Myleran. BCNU reduced pluripotent stem cells to 40% and erythroid progenitors to less than 5% of normal. B-8, the earliest erythroid progenitors, regenerated without erythropoietin (Epo) completely within 5 days. At 14 days after BC...

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Mature bone marrow erythroid burst-forming units do not require T cells for induction of erythropoietin-dependent differentiation

Cell-cell interactions between mature T cells and peripheral blood null cells induce erythropoietin-stimulated differentiation of peripheral blood-derived erythroid progenitors. By the use of complement-fixing cytolytic murine hybridoma and antibody uniquely reactive with mature T lymphocytes, this dependence of immature peripheral blood erythroid burst-forming unit (BFU-E) differentiation upon...

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Evaluation of hematopoietic cells and myeloid/erythroid ratio in the bone marrow of the pheasant (Phasianus colchicus)

In order to study the normal hematopoiesis, cellular components and myeloid/erythroid (M/E) ratio in the bone marrow of the pheasant (Phasianus colchicus), bone marrow samples were collected from the proximal tibiotarsus bone of 16 clinically healthy adult pheasant. The bone marrow smears were stained using the Giemsa stain. The results indicated that the development and formation of b...

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ژورنال

عنوان ژورنال: Experimental & Molecular Medicine

سال: 2007

ISSN: 2092-6413

DOI: 10.1038/emm.2007.31